Chimeric antigen receptor (CAR) therapy - Stock image

Germany, Antibody, Antigen, Biotechnology, Blood

Chimeric antigen receptor (CAR) therapy royalty-free stock photo
Chimeric antigen receptor (CAR) therapy royalty-free stock photo

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Stock photo ID:953850456
Upload date:May 04, 2018

Description

Engineered receptors on the surface of a T-lymphocyte bind specifically to CD19-antigen molecules on the surface of a leukemia cell. This activates a signal cascade in the T-cell leading to the segregation of vesicles that contain perforin and gramzymes molecules. The perforins build channels for the granzymes which enter the leukemia cell and activate finally the apoptosis (cell death) of the cancer cell.
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